Artificial Intelligence and Computational Drug Discovery and Development (AICOMPDRUG)

AICOMPDRUG 201  Techniques in Drug Discovery  (3 Units)  Fall  

Instructor(s): Brian ShoichetBrian Shoichet also teaches: BIOPHYSICS 297

Prerequisite(s): None.

Restrictions: This course is limited to students in the AICD3 Program and other PhD programs at UCSF.

Activities: Lecture

The course introduces widely used techniques in drug discovery. Students will engage with the social, economic, and structural elements that underpin the pharmaceutical industry and delve into the various phases and methodologies involved in drug development. The course is structured to progressively build understanding from foundational concepts to advanced techniques, with each week dedicated to specific themes.

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  • School: Pharmacy
  • Department: Bioengineering And Therapeutic Sciences
  • May the student choose the instructor for this course? No
  • Does enrollment in this course require instructor approval? No
  • Course Grading Convention: Letter Grade
  • Graduate Division course: No
  • Is this a web-based online course? No
  • Is this an Interprofessional Education (IPE) course? No
  • May students in the Graduate Division (i.e. pursuing Master or PhD) enroll in this course? Yes
  • Repeat course for credit? No

AICOMPDRUG 202  PK/PD Principles  (2 Units)  Fall  

Prerequisite(s): None.

Restrictions: This course is limited to first year students in the AICD3 Program.

Activities: Lecture

This course is focused on introducing students to the basic principles of pharmacokinetics and pharmacodynamics. Foundational knowledge and concepts in absorption, distribution, metabolism, and excretion, dose-response relationship, and pharmacogenomics will be covered in a series of lecture-based classes. This class provides the building block knowledge to another computational pharmacokinetics/pharmacodynamics modeling class in the subsequent quarter.

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  • School: Pharmacy
  • Department: Bioengineering And Therapeutic Sciences
  • May the student choose the instructor for this course? No
  • Does enrollment in this course require instructor approval? No
  • Course Grading Convention: Letter Grade
  • Graduate Division course: No
  • Is this a web-based online course? No
  • Is this an Interprofessional Education (IPE) course? No
  • May students in the Graduate Division (i.e. pursuing Master or PhD) enroll in this course? Yes
  • Repeat course for credit? No

AICOMPDRUG 203  Fundamentals of Machine Learning  (5 Units)  Fall  

Instructor(s): Shenghuan Sun

Prerequisite(s): None.

Restrictions: This course is limited to first year students in the AICD3 Program.

Activities: Lecture, Seminar, Workshop

This course provides a comprehensive overview of computer programming fundamentals. It covers the essentials of programming languages and AI/ML tools pertinent to pharmaceutical sciences. Students will develop a foundational understanding of computational techniques. The course includes project-based assignments designed to simulate real-world drug discovery scenarios, offering practical experience with the computational methods and AI/ML tools explored throughout the course.

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  • School: Pharmacy
  • Department: Bioengineering And Therapeutic Sciences
  • May the student choose the instructor for this course? No
  • Does enrollment in this course require instructor approval? No
  • Course Grading Convention: Letter Grade
  • Graduate Division course: No
  • Is this a web-based online course? No
  • Is this an Interprofessional Education (IPE) course? No
  • May students in the Graduate Division (i.e. pursuing Master or PhD) enroll in this course? Yes
  • Repeat course for credit? No

AICOMPDRUG 204  Computation and AI in Drug Discovery and Development  (3 Units)  Winter  

Instructor(s): AMITA JOSHI

Prerequisite(s): None.

Restrictions: This course is limited to first year students in the AICD3 Program.

Activities: Lecture

This course provides examples of the application of computation and artificial intelligence (AI) at various stages in drug discovery and development. Key aspects of the course include a stepwise progression through this process with case examples covering drug discovery powered by AI and machine learning (ML) in target identification and drug design, model-informed drug development, applications of AI in disease modeling and precision medicine.

View full course details:

  • School: Pharmacy
  • Department: Bioengineering And Therapeutic Sciences
  • May the student choose the instructor for this course? No
  • Does enrollment in this course require instructor approval? No
  • Course Grading Convention: Letter Grade
  • Graduate Division course: No
  • Is this a web-based online course? No
  • Is this an Interprofessional Education (IPE) course? No
  • May students in the Graduate Division (i.e. pursuing Master or PhD) enroll in this course? Yes
  • Repeat course for credit? No

AICOMPDRUG 205  Modeling for Drug Development  (4 Units)  Winter  

Instructor(s): Rada Savic

Prerequisite(s): This course is limited to first year students in the AICD3 Program.

Restrictions: None.

Activities: Lecture, Project, Workshop

Students will delve deeply into the principles of population PK-PD modeling, with an emphasis on how these models can be leveraged to improve successes at every stage of drug development. Additionally, the course will explore how PK-PD models assist clinicians in optimizing drug treatment strategies. The integration of AI with traditional PK-PD methods will also be introduced, highlighting its potential to further enhance model-informed drug development.

View full course details:

  • School: Pharmacy
  • Department: Bioengineering And Therapeutic Sciences
  • May the student choose the instructor for this course? No
  • Does enrollment in this course require instructor approval? No
  • Course Grading Convention: Letter Grade
  • Graduate Division course: No
  • Is this a web-based online course? No
  • Is this an Interprofessional Education (IPE) course? No
  • May students in the Graduate Division (i.e. pursuing Master or PhD) enroll in this course? Yes
  • Repeat course for credit? No

AICOMPDRUG 206  RWD/RWE Mining and Analysis  (4 Units)  Spring  

Instructor(s): Michelle Wang

Prerequisite(s): None.

Restrictions: None.

Activities: Lecture, Project, Workshop

This course offers a deep dive into the application of Artificial Intelligence (AI) and Real-World Data (RWD)/Real-World Evidence (RWE) in modern healthcare settings. The course combines theoretical learning with practical workshops, spanning advanced natural language processing, language models, to multi-modal approaches. Students will explore the complexities of RWE/RWD, including data sources, challenges, and their pivotal role across drug development and clinical care.

View full course details:

  • School: Pharmacy
  • Department: Bioengineering And Therapeutic Sciences
  • May the student choose the instructor for this course? No
  • Does enrollment in this course require instructor approval? No
  • Course Grading Convention: Letter Grade
  • Graduate Division course: No
  • Is this a web-based online course? No
  • Is this an Interprofessional Education (IPE) course? No
  • May students in the Graduate Division (i.e. pursuing Master or PhD) enroll in this course? Yes
  • Repeat course for credit? No

AICOMPDRUG 207  Advanced Omics Analysis and Systems Pharmacology  (4 Units)  Spring  

Prerequisite(s): None.

Restrictions: None.

Activities: Lecture, Project, Workshop

This course provides an in-depth exploration of omics data analysis, emphasizing the integration of advanced Artificial Intelligence (AI) and Machine Learning (ML) techniques. Students will gain an understanding of omics research, its applications in systems biology, and the challenges of integrating multi-modal data to derive actionable insights.

View full course details:

  • School: Pharmacy
  • Department: Bioengineering And Therapeutic Sciences
  • May the student choose the instructor for this course? No
  • Does enrollment in this course require instructor approval? No
  • Course Grading Convention: Letter Grade
  • Graduate Division course: No
  • Is this a web-based online course? No
  • Is this an Interprofessional Education (IPE) course? No
  • May students in the Graduate Division (i.e. pursuing Master or PhD) enroll in this course? Yes
  • Repeat course for credit? No

AICOMPDRUG 223A  AI and ML for Capstone Innovation  (3 Units)  Fall  

Instructor(s): Michael MotionMichael Motion also teaches: AICOMPDRUG 223B, AICOMPDRUG 223C

Prerequisite(s): None.

Restrictions: This course is limited to first year students in the AICD3 Program.

Activities: Lecture, Project, Discussion

This course offers students an immersive experience in the latest technological advancements, particularly in AI and machine learning, through literature reviews, guest lectures from industry leaders, and interactive discussions. Another significant focus is placed on providing students with a comprehensive overview of the various topics and areas of interest available for their capstone projects.

View full course details:

  • School: Pharmacy
  • Department: Bioengineering And Therapeutic Sciences
  • May the student choose the instructor for this course? No
  • Does enrollment in this course require instructor approval? No
  • Course Grading Convention: Letter Grade
  • Graduate Division course: No
  • Is this a web-based online course? No
  • Is this an Interprofessional Education (IPE) course? No
  • May students in the Graduate Division (i.e. pursuing Master or PhD) enroll in this course? Yes
  • Repeat course for credit? No

AICOMPDRUG 223B  Practical Modules of AI and ML for the Biotech Industry  (3 Units)  Winter  

Instructor(s): Michael MotionMichael Motion also teaches: AICOMPDRUG 223A, AICOMPDRUG 223C

Prerequisite(s): None.

Restrictions: This course is limited to first-year students in the AICD3 Program.

Activities: Lecture, Project, Discussion

This course offers students an immersive experience in the latest technological advancements, particularly in AI and machine learning, through literature reviews, guest lectures from industry leaders, and interactive discussions. Another significant focus is placed on providing students with a comprehensive overview of the various topics and areas of interest available for their capstone projects.

View full course details:

  • School: Pharmacy
  • Department: Bioengineering And Therapeutic Sciences
  • May the student choose the instructor for this course? No
  • Does enrollment in this course require instructor approval? No
  • Course Grading Convention: Letter Grade
  • Graduate Division course: No
  • Is this a web-based online course? No
  • Is this an Interprofessional Education (IPE) course? No
  • May students in the Graduate Division (i.e. pursuing Master or PhD) enroll in this course? Yes
  • Repeat course for credit? No

AICOMPDRUG 223C  AI and ML Research Frontiers  (3 Units)  Spring  

Instructor(s): Michael MotionMichael Motion also teaches: AICOMPDRUG 223A, AICOMPDRUG 223B

Prerequisite(s): None.

Restrictions: None.

Activities: Lecture, Seminar

This course explores cutting-edge research in AI and machine learning, focusing on their impact on drug discovery and development. Students will conduct background literature reviews and gain insights from industry and academic leaders through guest lectures, learning modules, and interactive discussions. Emphasizing diverse topics and innovative approaches, the course equips students to address real-world challenges with actionable solutions and prepares them for impactful Capstone Projects.

View full course details:

  • School: Pharmacy
  • Department: Bioengineering And Therapeutic Sciences
  • May the student choose the instructor for this course? No
  • Does enrollment in this course require instructor approval? No
  • Course Grading Convention: Letter Grade
  • Graduate Division course: No
  • Is this a web-based online course? No
  • Is this an Interprofessional Education (IPE) course? No
  • May students in the Graduate Division (i.e. pursuing Master or PhD) enroll in this course? Yes
  • Repeat course for credit? No