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Degree Offered: MAS (Master’s of Advanced Studies)
Program Leadership:
Elaine Ku, MD, MAS, Director
Admissions Inquiries:
Clair Dunne, Program Administrator
Program Description
Master's Degree Program in Clinical and Epidemiologic Research is a two-year program that through enhanced coursework and precepting provides trainees with mastery of clinical and epidemiologic research methods and culminates in a number of required products including a comprehensive literature review, a presentation at a national or international scientific conference, and publication of a peer-reviewed scientific paper.
For complete information on the Master‘s Degree Program in Clinical and Epidemiologic Research and degree tracks, please visit our website.
Admission Requirements
Possession of an undergraduate degree from an accredited institution with a minimum grade point average (GPA) of 3.0 (equal to a letter grade of "B"). Preference will be given to scholars who have demonstrated knowledge or experience in some aspect of a health-related field (e.g., clinical practice, public health, health promotion) by virtue of either possession of a graduate or professional doctoral degree (MD, DDS, PharmD, PhD or international equivalent), being currently enrolled in such a program, or relevant work experience. Although not required, this prior knowledge or experience is preferred because program scholars will be required to perform original research in an area of their choosing to fulfill graduation requirements. Prior substantive knowledge or experience in a health-related field can be very helpful in identifying a research area of interest and in maintaining motivation for the work.
Established relationship with a research mentor at UCSF, defined as a faculty member in either of the Schools of Medicine, Nursing, Pharmacy, or Dentistry. Scholars already at UCSF should have this established by the time of application. Those who are applying from outside UCSF should have this established by the beginning of the program. Applicants applying from outside UCSF are encouraged to identify and contact UCSF research mentors on their own or, after acceptance into the program, may request assistance from the TICR Program to help them identify a research mentor.
For scholars who are primarily based in other training programs or positions at UCSF, supervisor's assurance that at least 70% of time will be available August through May to divide between the activities of this program and the conduct of the trainee's clinical research projects.
Affirmation of the Professional Conduct Statement (signed during orientation).
Find application information on our website.
Learning Outcomes
To complete the program, scholars must satisfy program objectives, which are to:
- Acquire a mastery of a broad set of clinical research methods
- Plan and implement one or more clinical research projects that leads to a first-author publication
- Obtain experience in the instruction of clinical research methods
Additional Information
Career Outcomes
Degree Requirements
- Courses
At least 38 quarter-units of coursework are needed for graduation. Trainees will take the majority of their coursework in the first year allowing for focus on performing independent research in the second year. Grading policy is determined by the UCSF Graduate Division. In particular, scholars should note that UCSF graduate students must maintain at least a 3.0 (B average) and that letter grades cannot be converted to "S/U" after the deadline for the respective quarter. It is the policy of the TICR Program that one "C" grade or less (or one "U" grade) will trigger a discussion between the program director and the student about the expected level of performance in the program. Two or more grades of "C" or less (or two or more "U" grades) will trigger a formal review by the program and the chair of the scholars’ Master’s Committee. This formal review will develop an individualized remediation plan to address the deficiencies. A memorandum of understanding will be generated that clearly outlines specific steps and associated timeline that the scholar must fulfill in order to return to satisfactory performance. The memorandum will be signed by the following parties: the scholar, the Master’s Committee chair, and the program director. Should a scholar be unable to fulfill the expectations according to the timeline outlined in the memorandum, the student will be subject to dismissal from the program.
- Accomplishment of the Following Products of Clinical Research:
- Comprehensive literature critique: Each master’s student composes a systematic review and critique of the literature pertinent to a specific research question (or set of related questions) in his or her research field, culminating in a five to 10-page report that demonstrates a mastery of the field’s literature. The fundamental objective of this requirement is for the scholar to demonstrate that he or she can evaluate a number of papers/reports regarding a particular substantive question (or set of related questions), provide high-level critique of the threats to validity in the individual papers and then come to a conclusion about the question(s) in hand. The critique must have a methods section detailing the process for identifying and analyzing the articles. The report should be undertaken with an eye toward formal publication, but this is not required. Students are expected, although not required, to complete this requirement by the end of the first year.
- First-authored oral or poster presentation at a national or international meeting: Students are required to submit a first-authored abstract to a nationally or internationally recognized scientific meeting/conference within the scholar's academic field and have that abstract accepted for either poster or oral presentation. It may be acceptable in selected cases, with pre-approval by the scholar's master’s committee, to present work that was started prior to enrollment in the program. It is expected that the work represents a substantive contribution to the scholar's research field.
- Submission as first author of a peer-reviewed manuscript: Using data analyzed (but not necessarily collected) during residence in the master's program, students must prepare and submit a first-authored manuscript for publication in a peer-reviewed journal that is approved by the master’s committee. It may be acceptable in selected cases, upon approval of the scholar's committee, to submit work that was started prior to enrollment in the program. The manuscript may be a comprehensive extension of the work submitted in abstract form to a national meeting. It is expected that the work represents a substantive contribution to the scholar's research field.
3. Instructional Experience in Clinical Research:
The following requirements follow the natural progression of a research project, from a review of the existing literature to publication. Each element of the required work is relevant to student’s research productivity and enhances his or her credibility as an emerging researcher. Before embarking on these products, scholars should have their concepts approved by each member of his or her master’s committee.
Core Courses
Program of Study for the Master‘s Degree Program in Clinical and Epidemiologic Research
See a sample course schedule.
Tracks
The master’s degree program currently has two optional tracks of specialized instruction in which scholars can elect to enroll. There is one track in Data Science in Clinical Research and one track in Implementation Science. Scholars in these tracks will be required to take the core set of courses in epidemiologic and biostatistical methods that underlie clinical research and will use their elective courses for focused instruction in their track’s specific objectives. Scholars may choose to join these tracks at any time during their residence in the program.
Data Science in Clinical Research Track
Data Science in Clinical Research is an emerging discipline — for which there is not a standard definition — in response to the explosion of available and complex data in biomedicine and related streams. Examples of complex data include those from the laboratory (e.g., genomics and other “-omics”), biomedical imaging, electronic medical records, and other “found” data (e.g., social media). The TICR Program believes data science in the context of clinical research is best understood as an interdisciplinary hybrid of the fields of informatics, computer science, biostatistics, and epidemiology. As such, a data scientist has a broad background and expertise in accessing data, manipulating data, and forming inferences (i.e., summarizing raw data into meaningful messages) from data. A data scientist may typically not have as deep an expertise as a dedicated computer scientist, bio/clinical informatician, biostatistician, or epidemiologist in their respective fields, but instead she/he brings unique value because of his/her broad skill set accessing complex data, manipulating complex data, visualizing complex data, and being able to perform a broad array of analytic techniques.
The Data Science in Clinical Research Track of the master’s degree program is tailored for researchers who seek to work in complex data environments (sometimes referred to as “Big Data”) and who desire to become facile in the manipulation of large (and perhaps unstructured and unwieldy) data structures and the summarization of data into meaningful messages. Coursework in the track extends upon the basic foundation of epidemiology and biostatistics in the base master’s degree program to include required and elective courses in advanced data manipulation, prediction, clustering/pattern recognition and data reduction. The Data Science in Clinical Research Track distinguishes itself from other data science training programs by being embedded into the context of human subjects-based health-related research and a solid base of epidemiology and clinical research. Many of the contextual examples used in the courses and student projects are from the life sciences and clinical care. Graduates of the Data Science in Clinical Research Track are poised to work in either leadership or supportive roles in academia, industry, or municipal health systems.
Implementation Science Track
Implementation science (IS) aims to improve the adoption of evidence-based practices and policies in clinical care and public health, and the development of best evidence through community engagement. The master's program IS Track responds to the increasing concern of the World Health Organization (WHO), U.S. National Institutes of Health and Institute of Medicine that the tremendous advances we have achieved in developing effective tests, treatments and preventive measures are not being fully translated into improved population health. IS research relates to the second arm of what is popularly known as translational research: the first arm ("T1") being the translation of knowledge from the laboratory to human subjects, and the second arm ("T2") involving the translation of clinical research (behaviors, therapies, or devices) into practice in real-world settings.
The IS Track is ideal for researchers who plan to pursue the development, implementation or evaluation of policies, practice-based interventions and/or community-based programs designed to:
- improve uptake/safety/quality/access;
- reach diverse populations;
- reduce the overuse of diagnostic tests or treatments; or
- provide preventative medicine or health promotion programs.
Coursework in the track is guided by a conceptual framework that illustrates the different groups and organizations targeted by implementation research, and emphasizes the importance of interdisciplinary collaboration and community participation for the effective translation of evidence into practice. Master's program scholars who elect the IS Track typically begin coursework in the spring quarter of their first year and typically enroll in at least one IS course per quarter during the second year. In addition to course requirements, IS Track scholars receive career mentoring and specialized feedback on their research protocols. Scholars completing this track may list "Master of Advanced Study, Clinical Research with Specialization in Implementation Science" on their curriculum vitae.
The IS Track is co-sponsored by the UCSF Implementation Science Program and is directed by Dr. Maria Garcia and Dr. Priya Shete . One distinction of IS research is its emphasis on multidisciplinary collaboration and teamwork. The IS track increases scholars' exposure to and contact with a broad spectrum of UCSF faculty conducting IS research — an important step in developing a research network that scholars can call upon throughout their careers.
Clinical Informatics Track - New for 2024-2025
For current details of this track, please visit our curriculum page.